Available from: https://mpns.science.kew.org/mpns-portal/ (Last accessed on May 10, 2023). Mohammed Al Mana College for Health Sciences (MACHS), Saudi Arabia. Television match official: (2003). Analysis of cutaneous adverse drug reactions reported at the regional ADR monitoring center. Ginkgo biloba L. (5.1%), Combinations of Clematis spp.+ Prunella vulgaris L. + Trichosanthes kirilowii Maxim. Sign up for exclusive newsletters, comment on stories, enter competitions and attend events. Botanical nomenclature in pharmacovigilance and a recommendation for standardisation. Multiple criteria for seriousness were reported in 13 out of 241 ICSRs. Regul. Causative drugs: cutaneous ADRs where at least one TM was mentioned as a suspected drug were considered. Artemisia argyi H.Lv. Six Nations fixtures and results 2023 (all times GMT) Round 1. Saturday, June 24, 2023 - Group A United States 1-1 Jamaica - Soldier Field, Chicago, IL. Cutaneous ADRs: as per Medical Dictionary for Regulatory Activities (MedDRA, 2023), ICSRs in which the skin and subcutaneous tissue disorders was mentioned as system organ class (SOC) were considered as cutaneous ADRs. France entered the tournament as defending champions, having won the Grand Slam in 2022. Identified duplicate reports were provided with the same report id after VigiMatch was run by VigiBase. Wu, K. M., Farrelly, J. G., Upton, R., and Chen, J. Moreover, VigiBase uses various medical and drug classifications like WHO-Drug, MedDRA, WHO ICD, and WHO-ART for ensuring uniform structural data entry from various member countries. Brendon Pickerill (New Zealand), Player of the Match: Rugby fans can access expert commentary and watch the best moments. Jaco Peyper (South Africa) Please refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in, Standings for the 2023 Six Nations Championship, Find your bookmarks in your Independent Premium section, under my profile, The Six Nations culminates on Saturday 18 March. A system for reporting and evaluating adverse drug reactions of herbal medicine in Taiwan from 1998 to 2016. Six Nations fixtures and results 2023 (all times GMT) Round 1 Saturday, February 4 2:15pm: Wales 10-34 Ireland, Principality Stadium 4:45pm: England 23-29 Scotland. Keep up with whats happening in the World Cup, Top 14, 6 Nations and Champions Cup. Finn Russell (Scotland), Assistant referees: Make Eurosport your go-to source for all of the latest Rugby results. Drug Saf. The present study has several limitations. Traditional medicines were prescribed for various conditions. In a prospective study conducted by Niang et al. Freddie Steward (England), Assistant referees: Ireland won at the Millennium Stadium in a Six Nations match for the first time since, Scotland won three consecutive games against England for the first time since, With this win, Scotland moved up to fifth in the, Prior to this game, Ireland were ranked 1st in the men's. Ethnopharmacology Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1088841 This article is part of the Research Topic Safety and Toxicity Profiling of Herbal Drugs View all 6 Articles Frank Murphy (Ireland) BBC is not responsible for any changes. In duplicate reports, all information matched except the notifier. By clicking Sign up you confirm that your data has been entered correctly and you have read and agree to our Terms of use, Cookie policy and Privacy notice. If TMs were mentioned as concomitant and interacting drugs in ICSRs, such ICSRs were not considered. Our study is based on an analysis of spontaneously reported suspected ADRs from VigiBase. doi:10.1111/pbi.12419, Modi, A., Desai, M., Shah, S., and Shah, B. 14:23 Jun 27. In the current analysis, we have prepared a list of suspected TMs that may cause SJS/TEN. Ethics review was exempted for the study. [1] It is the culmination of the 2023 Cricket World Cup qualification process and will decide the final two participants for the 2023 Cricket World Cup. Front. 40 (8), 651661. The Six Nations championships come to an end on Super Saturday on March 18. In the present study, 46 (1.3%) cases of TM-induced SJS, TEN, and SJS-TEN overlap were reported over a period of 5years. Adverse drug reactions in hospitalized patients: Results of the FORWARD (facilitation of reporting in hospital ward) study. Toxicol. Italy are hoping to take their good form and avoid the wooden spoon, while Scotland are also on the rise under Gregor Townsend and are hopeful of a positive tournament. 8 (3-4), 315318. A review of issues of nomenclature and taxonomy of hypericumperforatum L. And kews medicinal plant names services. Authors could not get country-specific data from VigiBase hence, it would not be possible to assess whether regulated or unregulated TMs were causing suspected ADRs. Nair, S. S., and Varghese, S. A. Methods: All the ICSRs reported between 1st January 2016 and 30th June 2021 from the UN Asia region in VigiBase where at least one TM was suspected to cause cutaneous ADRs were included in the study. As TMs are misbelieved to be completely safe, spontaneous reporting of individual events is an important source of getting information on ADRs associated with them (Tabali et al., 2009). (2007). (4.8%), Combinations of Corydalis yanhusuo (Y.H.Chou and Chun C.Hsu) W.T.Wang ex Z.Y.Su and C.Y.Wu. doi:10.5772/64468, Fokunang, C. N., Ndikum, V., Tabi, O. Y., Jiofack, R. B., Ngameni, B., Guedje, N. M., et al. Stocks) Engl., Commiphora wightii (Arn.) doi:10.1007/BF03261975, Srirama, R., SanthoshKumar, J. U., Seethapathy, G. S., Newmaster, S. G., Ragupathy, S., Ganeshaiah, K. N., et al. If the above tiebreaker fails to separate tied teams, the team that scores the higher number of total tries (including penalty tries) in their matches is ranked higher. This article uses VigiBase as its data source. Christophe Ridley (England) Altern. All ICSRs where at least one TM was suspected of causing the cutaneous ADRs were considered. Walker, K., and Applequist, W. L. (2012). Phytomedicine 14 (4), 273279. Sports Mole provides in-depth previews and predictions for every match from the biggest leagues and competitions in world football. Copyright 2023 Barvaliya, Chetan, Chandan, Ray, Hegde, Unger, Patel and Roy. Data flow of suspected cutaneous ADRs with traditional medicines from VigiBase. 6 Nations 2023 News Table Fixtures Results Gonzalo Quesada to Coach Italy After 2023 Rugby World Cup 1 day ago by Ultimate Rugby Gonzalo Quesada will become Italy coach after the 2023 Rugby World Cup replacing Kieran Crowley, the Italian federation announced Friday. Interpretation: TMs are linked with various cutaneous ADRS ranging from pruritus to toxic epidermal necrolysis which may have serious consequences. Although, cutaneous ADRs are frequently mild and benign, their early diagnosis with withdrawal of the causative drug at the earliest is crucial for avoiding a more serious problem. (4.1), and Vitis vinifera (L.) (4%) were other commonly suspected TMs in reported suspected cutaneous reactions. Resources foracademics and university staff, Everything you need for each stepof your study abroad journey. Heres a look at the Womens Six Nations table and full results for 2023: 1. 14 (1), 821. Phytother. Brian MacNeice (Ireland), Player of the Match: Retrospective epidemiology data are therefore needed to determine the medications linked to the risk of suspected cutaneous ADRs. Ginkgo biloba L. was used for central nervous system, cardiovascular, and ear, nose and throat problems. The VigiMatch was used to identify duplicate information in a dataset based on matched and mismatched information between the pairs of reports through a statistical model (https://who-umc.org/research/vigimethods/). On the same day, Scotland beat England at Twickenham in the Calcutta Cup. Television match official: Caelan Doris (Ireland), Assistant referees: To the best of our knowledge, the list of TMs that may cause cutaneous ADRs including SJS/TEN is not available in the literature. doi:10.14260/jemds/2019/579, Niang, S. O., Tine, Y., Diatta, B. (2019). Background: Data on traditional medicine-induced cutaneous adverse drug reactions (ADRs) is very scarce. Ben O'Keeffe (New Zealand) and Vaniot., Ginko Biloba L., Vitis Vinifera L. were some commonly reported botanicals to cause skin-related ADRs in this analysis (Table 2). The related PTs as a group forms High-Level Term (HLT), which is again clubbed into High-Level Group Term (HLGT). Want to bookmark your favourite articles and stories to read or reference later? HH, BU, SKR, and TP contributed to manuscript revision and finalization. A total of 28,507 ICSRs were retrieved with TMs as suspected causative drugs with at least one suspected ADR from VigiBase for United Nations Asia region. The current secondary analysis based on the WHO database (VigiBase) of individual case safety reports (ICSRs) focuses on the suspected cutaneous ADRs linked to traditional medicines (TMs). The Six Nations championships come to an end on Super Saturday on March 18. Data were analyzed using the IBM SPSS software version 25.0. Few case reports have been published where SJS and TEN are reported with Ayurvedic and traditional medicines (Chowdhury et al., 2004; Shivamurthy et al., 2012; Jangra et al., 2020; Oluwo et al., 2020). Rash, pruritus, urticaria, SJS, angioedema, and eosinophilia were some commonly reported serious reactions. WebStay up to date with this season's Six Nations U20 standings. Death was reported in 5 ICSRs. Electric car batteries: just how bad are they for the environment? Ann. This secondary data analysis quantifies and characterizes suspected cutaneous ADRs connected to TMs that were spontaneously reported to the big data repository VigiBase. The lists of modern medicines causing various cutaneous ADRs have been available extensively in the literature and regularly updated through various sources of information that can guide clinicians in being careful while prescribing these drugs. ICSRs with missing notifier information were excluded from the analysis. Br. Drugs account for nine out of ten cases of SJS/TEN (Barvaliya et al., 2011; Patel et al., 2013). BMC Complement. However, such information is scarce for TMs. Artemisia argyi H.Lv. The authors obtained anonymized data from VigiBase through an agreement and the completion of required formalities with UMC, Sweden. For conventional pharmaceuticals, PV systems are well-established and integrated into healthcare and regulatory processes; however, this is not true for TMs (Barnes, 2003). ADRs leading to hospitalization/prolongation of hospitalization, life-threatening situations, disability, congenital malformation, and death of the patient were the various criteria for considering ADRs as serious; however, in the dataset, ADRs mentioned as serious without specifying the criteria for seriousness were considered. Cur Trad. Death was reported in 5 ICSRs. Sunday, June 25, 2023 - Groups A and B Trinidad & No data were available for these aspects so authors could not evaluate them for suspected ADRs. 2023 Gold Cup group stage. Eric Gauzins (France), Player of the Match: [2] In beating England in their final game on 18 March, Ireland completed a full set of consecutive victories over all the other tier-one international sides. Scotland beat England at Twickenham in the Calcutta Cup. The inclusion of plant species not mentioned on the product label in this instance may be the cause of cutaneous ADRs in connection with counterfeit herbal products. This suggests the importance of pharmacovigilance activities with TMs. View the methodology for Impact Rankings 2023: clean water and sanitation (SDG 6) The UKs University of Exeter leads the table. Six Nations 2023: Fixtures, schedule, kick-off times for England, Wales, Ireland, Scotland, France and Italy, Ireland beat Wales in Cardiff on Saturday, February 4. Reported criteria for the seriousness of ADRs. Ethics review was exempted for the study. doi:10.1111/bjd.13679, Oluwo, A. O., Irewole-Ojo, F. O., and Mabogunje, C. A. However, in most cases, the ingredients of medicines were not available. The overview of data flow is presented in Figure 1. Uppsala monitoring Centre: About VigiBase. Proper nomenclature is critical for accurately identifying the TMs implicated in ADR reports in a PV database (Wu et al., 2007). Toxic epidermal necrolysis after extensive dermal use of realgar-containing (arsenic sulfide) herbal ointment. Joy Neville (Ireland), Player of the Match: We use carefully calibrated indicators to provide comprehensive and balanced comparison across four broad areas: research, stewardship, outreach and teaching. FIGURE 2. News. (2015) in Africa, the authors, identified medicinal plant-related worsening of existing dermatitis, recurrence, and new onset dermatitis (Niang et al., 2015). The 2023 Guinness Six Nations takes place between February 4 and March 18 and will be of huge importance ahead of the Rugby World Cup in the autumn. doi:10.4314/ajtcam.v8i3.65276, Garcia-Doval, I., LeCleach, L., Bocquet, H., Otero, X. L., and Roujeau, J. C. (2000). WebView the methodology for Impact Rankings 2023: clean water and sanitation (SDG 6) The UKs University of Exeter leads the table. Get involved in exciting, inspiring conversations with other readers. 4, 92. doi:10.11604/pamj-cm.2020.4.92.26367, Onder, G., and Liperoti, R. (2016). WebBackground: Data on traditional medicine-induced cutaneous adverse drug reactions (ADRs) is very scarce. Television match official: Negative cutaneous effects of medicinal plants in Senegal. A., Diallo, M., Fall, M., Seck, N. B., et al. Ireland were second - losing only to the champions - while England, Scotland and Wales faltered. Andrew Brace (Ireland) Six Nations 2023 fixtures. Craig Evans (Wales) 7d ago Half time! Various cutaneous reactions like TEN and dermatitis have been reported with traditional Chinese medicines (Lim and Thirumoorthy, 2005; Sen et al., 2010; Wu and Deng, 2013). TMs listed as suspected offending agents in this analysis, should be kept in mind while dealing with suspected cutaneous ADRs. Six Nations 2023 odds. Saturday, In addition to identifying the plant components utilized and the preparation technique in the reports, and afterward, in VigiBase, the use of scientific binomial nomenclature, including botanical authority, is crucial (Farah et al., 2006; Dauncey et al., 2019). Here is the Six Nations table after round four: Join thought-provoking conversations, follow other Independent readers and see their replies. 2023 Eurosport, a Warner Bros. The commonly reported suspected cutaneous ADRs were itching, hair loss, dermatitis, rashes, hypopigmentation, nail disorder, lichenoid reaction, and suspected herbal drugs were Mahavat Vidhwansan, Dashmool Kwath/Mahavat Vidhwansan, Aloe, Mustard oil, Garlic, Menthol, Turmeric, Hypericum and unspecified herbal preparation (Kalaiselvan et al., 2015). Available from: https://www.meddra.org/how-to-use/basics/hierarchy (Last accessed on May 10, 2023). In 10 (0.3%) ICSRs, the reaction recurred after reintroducing suspected medicines. Six Nations Available from: https://www.who-umc.org/vigibase/vigibase/ (Last accessed on May 10, 2023). The present analysis does not prove that the suspected TM is directly linked to the particular ADR. This account already exists. Mon Mar 13 2023 - 07:36. doi:10.1111/jphp.12831, de Boer, A., Hunsel, Fvan., and Bast, A. The list includes 702 institutions from 84 countries/regions. doi:10.7861/clinmedicine.13-1-7, Sen, P., Ho, M. S., Ng, S. K., and Yosipovitch, G. (2010). Drug-induced stevens-johnson syndrome (SJS), toxic epidermal necrolysis (ten), and SJS-TEN overlap: A multicentric retrospective study. doi:10.1007/s12231-012-9211-6. doi:10.1016/j.phymed.2006.05.009, Wu, M. L., and Deng, J. F. (2013). The most frequently reported TMs associated with cutaneous ADRs are included in Table 2. Indications for which traditional medicines causing >1% cutaneous ADRs. Clinicians should be more vigilant in detecting and reporting events associated with TMs. Saturday, June 24, 2023 - Group A United States 1-1 Jamaica - Soldier Field, Chicago, IL. This table on SDG 6 clean water and sanitation measures universities research related to water, their water usage and their commitment to ensuring good water management in the wider community. Few reports with unspecified TMs without mentioning ingredients have also been found in the dataset. A history of allergic reactions to TMs should be considered to prevent ADRs. No use, distribution or reproduction is permitted which does not comply with these terms. Med. Italy return to the Six Nations after winning their first match in the tournament since 2015 against Wales last year. Ben O'Keeffe (New Zealand) Bhandari., Glyccine max (L.) Merr., Andrographis paniculata (Burm.f) Nees., Phyllanthus amarus Sch. TMs could cause rare but serious cutaneous ADRs like SJS/TEN. Quality control and strict legislation are required. Tom Foley (England), Player of the Match: England. TABLE 1. (Lausanne) 5, 167. doi:10.3389/fmed.2018.00167, Keywords: traditional medicines, vigibase, pharmacovigilance, Stevens-Johnson syndrome, cutaneous adverse drug reactions, signal, spontaneous reporting, Citation: Barvaliya MJ, Chetan AC, Chandan N, Ray SK, Hegde HV, Unger BS, Patel TK and Roy S (2023) Suspected cutaneous adverse drug reactions reported with traditional medicines: analysis of data for United Nations Asia region from WHO VigiBase. Karl Dickson (England) Indian J. Dermatol 64 (3), 250. doi:10.4103/ijd.IJD_682_16. Pharmacol., 30 May 2023 Sec. Therefore, we expect and welcome regular change in the ranked order of institutions (and we discourage year-on-year comparisons) as universities continue to drive this urgent agenda. Ireland won the tournament for a 15th time, along with a 13th Triple Crown and a fourth Grand Slam; it was also the first time they won the title in Dublin. This was the 100th meeting between France and Scotland. Australias Western Sydney University and the University of the Sunshine Coast come up in second and third. Pharmacol. There were 46 cases of Stevens-Johnson syndrome and toxic epidermal necrolysis reported with TMs during the study period. Preview: Beijing Guoan vs. Shanghai Port - prediction, team news, lineups, Preview: Colo-Colo vs. Dep. Background: Data on traditional medicine-induced cutaneous adverse drug reactions (ADRs) is very scarce. Almost 7% of cutaneous suspected ADRs due to TMS were reported as serious in the WHO database. Age distribution of patients with cutaneous ADRs. In a large dataset, common (>1%) ADRs and medicines were presented in the analysis. Andrea Piardi (Italy) This list will be helpful to clinicians in evaluating the previous drug history while assessing the case of SJS/TEN. doi:10.1111/j.1365-4632.2010.04497.x. Front. doi:10.1016/j.hermed.2015.01.006, Kumar, R., Das, A., and Das, S. (2018). (Lond). The age distribution of patients with cutaneous ADRs linked to various TMs is shown in Table 1. France won against England at Twickenham for the first time since, France scored their most points against England (previously 37 points in, This was England's heaviest defeat at home (43-point difference), surpassing the 36 points to, This was England's heaviest defeat in any Home, Five or Six Nations match, surpassing the 4313 loss to Ireland in, Ireland become the first team to record 80 wins across all editions of the. Adverse food-drug interactions. doi:10.1016/j.yrtph.2015.10.009, Farah, M. H., Olsson, S., Bate, J., Lindquist, M., Edwards, R., Simmonds, M. S., et al. (2019). (2018). Follow the top England and France rugby news stories and find the most up to date Six Nations results, standings, top scorers and previous winners. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Ben Whitehouse (Wales), Assistant referees: J. Dermatol 173 (2), 2629. SJS and TEN are uncommon but are severe forms of cutaneous ADRs that negatively impact the patients quality of life (Sharma et al., 2001). News June 24, 2023 8:51 pm (GMT) by Guinness Six Nations The World Rugby Under-20 Championship kicked off in thrilling fashion as England rescued an impressive draw against Under-20 Six Nations Grand Slam holders Ireland before Wales pushed six-time tournament winners New Zealand to the limit. Australias Western Sydney University and the 2011-2023 Sports Mole Ltd. All rights reserved. Six Nations table 2023 Position Team Played Won Drawn Lost PF PA PD Bonus PTS 1 Ireland 1 1 0 0 34 10 +24 1 5 2 Scotland 1 1 Singap. 47, 9599. doi:10.1002/dta.1929, Vickers, K. A., Jolly, K. B., and Greenfield, S. M. (2006). 44 (1), 134135. Tottenham 'add Micky van de Ven to transfer shortlist', Newcastle United 'closing in on Sandro Tonali deal', David de Gea's Man United future 'still in the balance', Preview: Belgrano vs. Banfield - prediction, team news, lineups. The incidence of suspected cutaneous ADRs is 1%3% in developed countries and 2%5% in developing countries (Modi et al., 2019). Based on MedDRA PT, pruritus (29.6%) was the most reported event, followed by a rash (20.3%) and urticaria (18.9%). Sunday March 12 sees Scotland welcome Ireland for a Celtic clash (3pm). They were reported in VigiBase across all the age groups, with preponderance in the 4564years age group. Enter your password to log in. Adverse effects of herbal medicines: An overview of systematic reviews. Adverse reactions to herbal products: An analysis of spontaneous reports in the database of the Pharmacovigilance Programme of India. 8 (3), 284295. 2:15pm: Wales 10-34 Ireland, Principality Stadium 4:45pm: England 23-29 Scotland, Twickenham Sunday, February 5. 71 (1), 414. TV: BBC. The Times Higher Education Impact Rankings are the only global performance tables that assess universities against the United Nations Sustainable Development Goals (SDGs). Regulations of TMs are a major concern, and they also vary from country to country. France scored 21 in the tournament and Ireland have 16. All authors contributed to the article and approved the submitted version. Drug Saf. doi:10.4103/0378-6323.110749, Posadzki, P., Watson, L. K., and Ernst, E. (2013). There is a possibility of underreporting. Jack Dempsey (Scotland), Assistant referees: The skin is more commonly involved system in suspected ADRs. VigiBase is a WHO global database of documented suspected ADRs in the form of individual case safety reports (ICSRs) (https://who-umc.org/vigibase/). Arsenal 'submit British-record 105m bid for Declan Rice'. Data indicates that TMs could cause a wide range of cutaneous ADRs from pruritus, rash, and urticaria to angioedema, SJS, and TEN. Bot. Amongst these, 6.8% of ICSRs were reported as serious. Med. Please review our, You need to be a subscriber to join the conversation. WebThe 2023 ICC Men's Cricket World Cup Qualifier is the 12th edition of the Cricket World Cup Qualifier, which is taking place in June and July 2023 in Zimbabwe. An earlier retrospective study reported the occurrence of maculopapular exanthema, exfoliative dermatitis, SJS, TEN urticaria, Drug Hypersensitivity Syndrome (DHS), angioedema, and fixed drug eruption amongst patients who received polyherbal formulation (Nair and Varghese, 2019). FIGURE 3. You can opt-out at any time by signing in to your account to manage your preferences. Wales 10-34 IrelandEngland 23-29 Scotland, Italy vs Ireland (2.15pm)Wales vs England (4.45pm), Italy vs Wales (2.15pm)England vs France (4.45pm), Scotland vs Italy (12.30pm)France vs Wales (2.45pm)Ireland vs England (5pm), France's Antoine Dupont raises the Six Nations trophy in 2022, Transfer Centre LIVE! Angus Gardner (Australia) The UK and Australia are the most-represented nations in the top 100 with 12 each. Scotland then backed up their Round 1 win with a convincing victory at home to Wales on the same day. MedDRA (2023). World Rugby Under-20 Championship: Day One Review. Detailed information about their frequency, severity, and long-term impact on health is lacking because of the high number of unreported cases. However, the involvement of TMs alone or its combinations with conventional pharmaceuticals in suspected ADRs are made possible by spontaneous ADR reporting and active surveillance, through pharmacovigilance centers (Skalli and Soulaymani, 2012). Marius Jonker (South Africa), Player of the Match: TABLE 3. Ireland rugby fans suggest songs to sing in stands, Ireland Sevens beat Great Britain in European Games final to qualify for Olympics, Warren Gatland says Wales players put in hoods and doused in water in preparation for World Cup, Ireland womens Under-20 side to travel to Italy next month for series of training matches, Richie Murphy makes four changes to Under-20s side for World Championship clash with Australia, Irish Sevens team into semi-finals at European Games with Olympic qualification up for grabs, An impressive performance: seven of eight Irish universities rise in international rankings, Garda treating Co Donegal missing persons case as probable murder investigation, Fintan OToole: Ryan Tubridy chose silence instead of speaking out. 6 Articles, This article is part of the Research Topic, https://doi.org/10.3389/fphar.2023.1088841, https://who-umc.org/media/yzpnzmdv/umc_caveat.pdf, https://mpns.science.kew.org/mpns-portal/, https://www.meddra.org/how-to-use/basics/hierarchy, https://who-umc.org/research/vigimethods/, https://www.who-umc.org/vigibase/vigibase/.
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